Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559089 | 0.89 | CA1 (0.67) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL926010 | 0.82 | — | — | |
| SCHEMBL132367 | 0.82 | LMNA (0.73) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL3842531 | 0.82 | LMNA (0.73) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL9126141 | 0.82 | LMNA (0.73) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL8414299 | 0.81 | LMNA (0.65) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL1534350 | 0.81 | ALDH1A1 (0.61) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL5697509 | 0.81 | SRD5A2 (0.59) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL7995493 | 0.81 | LMNA (0.55) | CA1CA2LMNASRD5A2MAPT | |
| SCHEMBL20679817 | 0.80 | KMT2A (0.69) | CA1CA2LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077866-A | EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | disclosed |