Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285844 | 0.73 | TDP1 (0.46) | ALDH1A1HIF1AMEN1KMT2ACYP3A4 | |
| SCHEMBL11691049 | 0.69 | ALDH1A1 (0.51) | ALDH1A1HIF1AAPPMEN1KMT2A | |
| SCHEMBL420859 | 0.69 | IKBKB (0.41) | ALDH1A1APPMEN1KMT2ACYP1A2 | |
| SCHEMBL31219322 | 0.68 | ALDH1A1 (0.55) | ALDH1A1HIF1AAPPMEN1KMT2A | |
| SCHEMBL8202301 | 0.67 | ALDH1A1 (0.47) | ALDH1A1APPMEN1KMT2ACA12 | |
| SCHEMBL7432122 | 0.67 | PTPRC (0.47) | ALDH1A1APPMEN1KMT2ACYP1A2 | |
| SCHEMBL20220262 | 0.67 | CA1 (0.45) | APPMEN1KMT2ACA12CA1 | |
| SCHEMBL8994176 | 0.67 | CES2 (0.37) | — | |
| SCHEMBL1513142 | 0.66 | APP (0.50) | ALDH1A1HIF1AAPPCA12CA1 | |
| SCHEMBL28198 | 0.66 | CA1 (0.67) | ALDH1A1APPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048863-A | SEXUAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5817819-A | GONADOTROPIN-RELEASING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-06 | — | — | US | disclosed |