Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027495 | 0.82 | MEN1 (0.47) | CYP3A4ALOX5ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4146714 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ATMALOX5ALDH1A1 | |
| SCHEMBL30030734 | 0.82 | MEN1 (0.47) | CYP3A4ALOX5ALDH1A1HSD17B10TDP1 | |
| SCHEMBL18103322 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ATMALOX5ALDH1A1 | |
| SCHEMBL8259845 | 0.82 | NPC1 (0.46) | CYP3A4ABCG2ATMALOX5ALDH1A1 | |
| SCHEMBL9908794 | 0.82 | CYP3A4 (0.46) | CYP3A4ATMALOX5ALDH1A1HSD17B10 | |
| SCHEMBL2022289 | 0.82 | CD44 (0.46) | CYP3A4ALOX5ALDH1A1KDM4EMAPT | |
| SCHEMBL4594563 | 0.82 | ALDH1A1 (0.42) | CYP3A4ALOX5ALDH1A1MAPTMEN1 | |
| SCHEMBL8525889 | 0.81 | ALDH1A1 (0.47) | ATMALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL13754300 | 0.80 | ACHE (0.41) | CYP3A4ALDH1A1HSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115641-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023249473-A1 | ANTIBODY-DRUG CONJUGATE WITH TWO TYPES OF DRUG-LINKER CONJUGATES ON SINGLE ANTIBODY | 주식회사 피노바이오 | 2023-12-28 | — | — | WO | disclosed |
| WO-2023214849-A1 | CONJUGATE OF DDX5 PROTEIN-BINDING CAMPTOTHECIN-BASED DRUG LINKED TO ACID-SENSITIVE LINKER AND IMMUNOCONJUGATE USING SAME | 주식회사 피노바이오 | 2023-11-09 | — | — | WO | disclosed |
| US-20230331715-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | VANDERBILT UNIVERSITY | 2023-09-28 | — | — | US | disclosed |
| US-11691980-B2 | Liphagal analog and multi-targeted kinase inhibitor containing liphagal or analog thereof | TOHOKU UNIVERSITY (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-29 | — | — | US | disclosed |
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | disclosed |
| US-20220024944-A1 | COMPOUNDS TARGETING MUTANT CALRETICULIN | MYELOPRO DIAGNOSTICS AND RESEARCH GMBH (AT) | 2022-01-27 | — | — | US | disclosed |
| WO-2022006228-A1 | ISOQUINOLINE DERIVATIVES, METHODS OF SYNTHESIS AND USES THEREOF | PROSETTA BIOSCIENCES, INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| US-7259229-B2 | Electroactive fluorene polymers having perfluoralkyl groups, process for preparing such polymers and devices made with such polymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-21 | — | — | US | disclosed |
| US-7230070-B2 | Electroactive fluorene copolymers and devices made with such polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-7220820-B2 | Electroactive fluorene copolymers and devices made with such polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-7214763-B2 | Electroactive fluorene copolymers and devices made with such polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-7211643-B2 | Electroactive fluorene copolymers and devices made with such polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-01 | — | — | US | disclosed |
| US-7183365-B2 | Electroactive fluorene polymers having perfluoroalkyl groups, process for preparing such polymers and devices made with such polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183366-B2 | Aromatic copolymers from dihalofluorene compounds and another dihalo- or diborono- aromatic monomers; organic electroluminescent polymers for use in light-emitting diodes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-27 | — | — | US | disclosed |
| WO-2004089925-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SEMAFORE PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3962415-A | Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer | AIRWICK INDUSTRIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, PKD1 | CYP3A4 221/4885ABCG2 1247/4885ATM 3836/4885 |
| US-20230331715-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, NR1I3, NR1H4 | CYP3A4 62/4885ABCG2 1045/4885ATM 4000/4885 |
| US-11691980-B2 | Liphagal analog and multi-targeted kinase inhibitor containing liphagal or analog thereof | STK16, STK3, STK4 | CYP3A4 4614/4885ABCG2 4496/4885ATM 134/4885 |
| US-20230303552-A1 | ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS | CHRM5, CHRM1, CHRM2 | CYP3A4 641/4885ABCG2 204/4885ATM 1324/4885 |
| US-20220024944-A1 | COMPOUNDS TARGETING MUTANT CALRETICULIN | CALR, MCL1, CALD1 | CYP3A4 4829/4885ABCG2 1572/4885ATM 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.