Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.65 |
| ▸ | ACE | P12821 | 5/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP7 | P09237 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | CPA1 | P15085 | 3/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829671 | 0.95 | MME (0.69) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL6416478 | 0.90 | MMP1 (0.64) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL9069169 | 0.89 | MME (0.66) | MMEACECPA1ACE2 | |
| SCHEMBL19292528 | 0.88 | ACE (0.70) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL15692369 | 0.88 | PSMB5 (0.68) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL17996007 | 0.88 | ACE (0.70) | MMEACEMMP2MMP7MMP9 | |
| Glycylleucylphenylalanine SCHEMBL4281374 | 0.87 | ACE (0.62) | MMEACEMMP2MMP7MMP9 | |
| Glycylleucylphenylalanine SCHEMBL4281369 | 0.87 | ACE (0.62) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL7365144 | 0.87 | ACE (0.73) | MMEACEMMP2MMP7MMP9 | |
| SCHEMBL15649671 | 0.87 | MME (0.67) | MMEACEMMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728144-B1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES | DARWIN DISCOVERY LTD (GB) | 2000-01-19 | — | — | EP | claimed |
| US-4613587-A | 2-MERCAPTOACETYL-PHENYLALANINE-LEUCINE AS ENZYME INHIBITOR, GENTAMICIN ANTIBIOTIC | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1986-09-23 | — | — | US | disclosed |