Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005362 | 1.00 | TRPV4 (0.41) | TRPV4PARP10PARP15PARP2FFAR4 | |
| SCHEMBL8014679 | 0.95 | TRPV4 (0.41) | TRPV4PARP10PARP15PARP2FFAR4 | |
| SCHEMBL8014677 | 0.95 | TRPV4 (0.41) | TRPV4PARP10PARP15PARP2FFAR4 | |
| SCHEMBL8017239 | 0.94 | ALDH1A1 (0.41) | TRPV4PARP10PARP15PARP2FFAR4 | |
| SCHEMBL8017235 | 0.94 | ALDH1A1 (0.41) | TRPV4PARP10PARP15PARP2FFAR4 | |
| SCHEMBL8013760 | 0.93 | ALDH1A1 (0.43) | TRPV4PARP10PARP15PARP2MAPT | |
| SCHEMBL8013763 | 0.93 | ALDH1A1 (0.43) | TRPV4PARP10PARP15PARP2MAPT | |
| SCHEMBL8005328 | 0.91 | TRPV4 (0.41) | TRPV4PARP10PARP15FFAR4KDM1A | |
| SCHEMBL8005326 | 0.91 | TRPV4 (0.41) | TRPV4PARP10PARP15FFAR4KDM1A | |
| SCHEMBL8005506 | 0.91 | PARP10 (0.46) | TRPV4PARP10PARP15FFAR4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |