Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16315984 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL16119083 | 0.96 | CNR2 (0.54) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL15711960 | 0.94 | ITGB3 (0.49) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL16118744 | 0.92 | ITGB3 (0.48) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL13260767 | 0.92 | ITGB3 (0.48) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL8005589 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1PPARGPTGES | |
| SCHEMBL16315983 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1PPARGPTGES | |
| SCHEMBL16119167 | 0.90 | CNR2 (0.49) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL14136469 | 0.88 | ITGB3 (0.45) | ITGB3ITGA2BCNR2CNR1KLK5 | |
| SCHEMBL16119287 | 0.88 | PTPN1 (0.52) | ITGB3ITGA2BKLK5PTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722923-B2 | Conjugates for treating neurodegenerative diseases and disorders | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-05-13 | — | — | US | disclosed |
| WO-2009101616-A9 | NOVEL CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-24 | — | — | WO | disclosed |
| WO-2009101616-A1 | NOVEL CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-08-20 | — | — | WO | disclosed |