Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16315983 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL8005403 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BPTPN1PPARGPTGES | |
| SCHEMBL15711960 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL16315984 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BPTPN1PPARGPTGES | |
| SCHEMBL7310540 | 0.90 | ACE (0.56) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL15111629 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL15111628 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL16119287 | 0.87 | PTPN1 (0.52) | ITGB3ITGA2BPTPN1ACEPPARG | |
| SCHEMBL6685168 | 0.86 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEITGA4 | |
| SCHEMBL6998950 | 0.86 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722923-B2 | Conjugates for treating neurodegenerative diseases and disorders | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-05-13 | — | — | US | disclosed |
| WO-2009101616-A9 | NOVEL CONJUGATES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-24 | — | — | WO | disclosed |
| WO-2005121069-A1 | LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005121070-A1 | LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2005-12-22 | — | — | WO | disclosed |