SCHEMBL8005425

SCHEMBL8005425

CC(N)C(=O)N(C(=O)C(N)Cc1ccccc1)C(O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALPI P09923 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ PTGS1 P23219 1/20 0.54
▸ XIAP P98170 1/20 0.54
▸ SLC7A5 Q01650 1/20 0.54
▸ SLC1A3 P43003 2/20 0.46
▸ SLC1A2 P43004 2/20 0.46
▸ SLC1A1 P43005 2/20 0.46
▸ CTRB1 P17538 1/20 0.45
▸ SLC15A1 P46059 1/20 0.44
▸ LTA4H P09960 2/20 0.44
▸ ANPEP P15144 2/20 0.44
▸ RNPEP Q9H4A4 2/20 0.44
▸ DNPEP Q9ULA0 2/20 0.44
▸ HPGD P15428 1/20 0.42
▸ SLC6A2 P23975 2/20 0.42
▸ TAAR1 Q96RJ0 2/20 0.42
▸ MAOA P21397 1/20 0.42
▸ SLC6A4 P31645 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6251230 0.90 SLC7A5 (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7593001 0.83 SLC7A5 (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1582659 0.81 LAP3 (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL11019330 0.80 SLC7A5 (0.48) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7292946 0.80 SLC15A1 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL10789698 0.79 SLC15A1 (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL10646229 0.79 SLC1A3 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29221573 0.78 MC4R (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8005620 0.78 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7592571 0.78 ALPI (0.48) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156555-A Method of preparing an enzyme participating in C-terminal amidation SHISEIDO COMPANY LTD. (JP) 2000-12-05 — — US disclosed
EP-0666318-B1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO CO LTD (JP) 2000-11-29 — — EP disclosed
US-5871995-A Purified enzymes participating in C-terminal amidation SHISEIDO COMPANY, LTD. (JP) 1999-02-16 — — US disclosed
EP-0884389-A1 Enzyme participating in C-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1998-12-16 — — EP disclosed
EP-0666318-A1 Enzyme participating in c-terminal amidation, and method of preparing same and use thereof SHISEIDO COMPANY LIMITED (JP) 1995-08-09 — — EP disclosed
EP-0438600-A1 ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF SHISEIDO COMPANY LIMITED (JP) 1991-07-31 — — EP disclosed
Send feedback