Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236560 | 0.87 | SLC6A2 (0.67) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL1164680 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL1164678 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL3960825 | 0.83 | OPRK1 (0.71) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL4176017 | 0.83 | OPRK1 (0.71) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL10313059 | 0.80 | ELANE (0.60) | LMNATDP1MEN1POLBKMT2A | |
| Oxalic Acid SCHEMBL1178218 | 0.79 | SLC6A3 (0.63) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| Oxalic Acid SCHEMBL1178219 | 0.79 | SLC6A3 (0.63) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL911193 | 0.77 | SLC6A2 (0.87) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 | |
| SCHEMBL911194 | 0.77 | SLC6A2 (0.87) | SLC6A2SLC6A3HTR3EHTR3BCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027790-A1 | MUTILIN COMPOUNDS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |