Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099260 | 0.84 | GRM5 (0.40) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL1072300 | 0.83 | TAAR1 (0.38) | KMT2AMEN1LMNATAAR1EPHX2 | |
| SCHEMBL18669321 | 0.83 | TAAR1 (0.38) | KMT2AMEN1LMNATAAR1EPHX2 | |
| SCHEMBL8005489 | 0.79 | TAAR1 (0.35) | KMT2AMEN1LMNATAAR1EPHX2 | |
| SCHEMBL8012170 | 0.79 | TAAR1 (0.35) | KMT2AMEN1LMNATAAR1EPHX2 | |
| SCHEMBL1071126 | 0.79 | EPHX2 (0.33) | KMT2AMEN1NPC1RAB9ATAAR1 | |
| SCHEMBL7997019 | 0.79 | NAMPT (0.38) | LMNAMDM2 | |
| SCHEMBL20310044 | 0.78 | GAA (0.33) | KMT2AMEN1NPC1RAB9APRMT5 | |
| SCHEMBL1072452 | 0.78 | GAA (0.33) | KMT2AMEN1NPC1RAB9APRMT5 | |
| SCHEMBL1070033 | 0.77 | GAA (0.35) | KMT2AMEN1NPC1RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108507-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2009-09-03 | — | — | WO | disclosed |