Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767671 | 0.82 | LSS (0.39) | NAMPTLSSABCC4MAPTALDH1A1 | |
| SCHEMBL21767675 | 0.82 | LSS (0.39) | NAMPTLSSABCC4MAPTALDH1A1 | |
| SCHEMBL30094731 | 0.81 | LSS (0.40) | NAMPTLSSABCC4MAPTALDH1A1 | |
| SCHEMBL2895285 | 0.81 | LSS (0.33) | NAMPTLSS | |
| SCHEMBL7996522 | 0.79 | LSS (0.36) | NAMPTLSSALDH1A1 | |
| SCHEMBL8005512 | 0.79 | KMT2A (0.36) | MDM2LMNA | |
| SCHEMBL3309650 | 0.78 | REN (0.31) | NAMPTLSS | |
| SCHEMBL3304630 | 0.78 | REN (0.31) | NAMPTLSS | |
| SCHEMBL1073190 | 0.77 | REN (0.33) | NAMPTLSSALDH1A1 | |
| SCHEMBL28559014 | 0.74 | TEAD3 (0.37) | NAMPTLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108507-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2009-09-03 | — | — | WO | disclosed |