Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005552 | 1.00 | MAPT (0.40) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL9069223 | 0.93 | MAPK10 (0.43) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8346366 | 0.92 | MAPT (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8346367 | 0.92 | MAPT (0.48) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL10479299 | 0.84 | APP (0.49) | MAPTCYP1A2NFE2L2PTGS2TTR | |
| SCHEMBL10479300 | 0.84 | APP (0.49) | MAPTCYP1A2NFE2L2PTGS2TTR | |
| SCHEMBL7993260 | 0.83 | MAPT (0.44) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8343851 | 0.83 | CYP19A1 (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7993262 | 0.83 | MAPT (0.44) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8346996 | 0.83 | TUBB4A (0.45) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | claimed |
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | disclosed |