Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12681587 | 0.77 | TSHR (0.38) | OPRK1OPRM1TSHRHDAC4ALDH1A1 | |
| SCHEMBL2662444 | 0.76 | SLC6A4 (0.41) | SLC6A4LMNATSHRALDH1A1 | |
| SCHEMBL31561698 | 0.75 | TSHR (0.33) | LMNATSHRALDH1A1 | |
| SCHEMBL3203338 | 0.75 | HTR2A (0.35) | LMNATSHRALDH1A1 | |
| SCHEMBL8790549 | 0.75 | CYP3A4 (0.36) | TAAR1LMNATSHRALDH1A1 | |
| SCHEMBL3203818 | 0.75 | TSHR (0.33) | LMNATSHRALDH1A1 | |
| SCHEMBL4482310 | 0.75 | HCAR2 (0.38) | TSHRHDAC4ALDH1A1PGR | |
| SCHEMBL8790706 | 0.75 | PBRM1 (0.40) | TAAR1SLC6A4LMNAOPRM1TSHR | |
| SCHEMBL8790711 | 0.75 | PBRM1 (0.40) | TAAR1SLC6A4LMNAOPRM1TSHR | |
| SCHEMBL10829203 | 0.73 | TSHR (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910744-B2 | Pyrazole and Pyrimidine groups are introduced on aromatic phosphine; (3-bromophenyl)methyl ketone and ethylene glycol cyclize to [3-(2-methyl-1,3-dioxolane-2-yl)phenyl]diphenylphosphane; adding hydrazine monohydrate, then oxidizing with hydrogen peroxide; [3-(3-Pyrazolyl)phenyl]diphenylphosphane oxide | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENT II KG (DE) | 2011-03-22 | — | — | US | disclosed |
| US-20090082203-A1 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | US | disclosed |
| US-20090082203-A1 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | US | disclosed |
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) | 2008-09-11 | — | — | US | disclosed |
| WO-2000008032-A1 | CATALYST LIGANDS USEFUL FOR CROSS-COUPLING REACTIONS | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082203-A1 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES | DDT, API5, MSL1 | TAAR1 1251/4885CRHBP 2580/4885CRHR2 4446/4885 |
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | SCLY, SELENOI, TST | TAAR1 754/4885CRHBP 4233/4885CRHR2 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.