Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133007 | 0.78 | MEN1 (0.48) | RAB9AKMT2ALMNAMAPTMEN1 | |
| SCHEMBL8133010 | 0.78 | MEN1 (0.48) | RAB9AKMT2ALMNAMAPTMEN1 | |
| SCHEMBL9735963 | 0.75 | MEN1 (0.50) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL9735955 | 0.75 | MEN1 (0.50) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL9735962 | 0.75 | MEN1 (0.50) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL8876005 | 0.68 | MEN1 (0.44) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL8876007 | 0.68 | MEN1 (0.44) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL18060097 | 0.64 | MEN1 (0.46) | KMT2ALMNAMAPTMEN1NPSR1 | |
| SCHEMBL15573909 | 0.64 | MEN1 (0.46) | KMT2ALMNAMAPTMEN1NPSR1 | |
| SCHEMBL3921874 | 0.64 | MAPT (0.67) | KMT2ALMNAMAPTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968162-A1 | 5-HYDROXYALKYL SUBSTITUTED PHENYLS AND THEIR USE IN MEDICAMENTS FOR THE TREATMENT OF ARTERIOSCLEROSIS AND HYPERLIPOPROTEINAEMIA | BAYER AG (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998034895-A1 | 5-HYDROXYALKYL SUBSTITUTED PHENYLS AND THEIR USE IN MEDICAMENTS FOR THE TREATMENT OF ARTERIOSCLEROSIS AND HYPERLIPOPROTEINAEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-13 | — | — | WO | disclosed |