Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006057 | 1.00 | GRM4 (0.39) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL8006061 | 1.00 | GRM4 (0.39) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL8016075 | 0.97 | DPP4 (0.38) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL8016078 | 0.97 | DPP4 (0.38) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL8016077 | 0.97 | DPP4 (0.38) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL1296115 | 0.81 | EPHX1 (0.41) | EPHX1HRH3GAA | |
| SCHEMBL12994226 | 0.80 | CTSK (0.34) | DPP4CTSKCTSSHRH3MEN1 | |
| SCHEMBL26460992 | 0.80 | EPHX1 (0.52) | EPHX1CTSKHRH3GAA | |
| SCHEMBL18457869 | 0.79 | GRM4 (0.44) | GRM4EPHX1DPP4CTSKCTSS | |
| SCHEMBL5328545 | 0.76 | EPHX1 (0.47) | EPHX1CTSKHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |