SCHEMBL800624

SCHEMBL800624

CCCCNCCOC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27425878 0.92 ALDH1A1 (0.65)
SCHEMBL27174196 0.90 ALDH1A1 (0.62)
SCHEMBL20878393 0.90 ALDH1A1 (0.62)
SCHEMBL27174199 0.90 ALDH1A1 (0.62)
SCHEMBL1532553 0.90 ALDH1A1 (0.62)
SCHEMBL19509413 0.90 ALDH1A1 (0.62)
SCHEMBL27174200 0.90 ALDH1A1 (0.62)
SCHEMBL20077441 0.90 ALDH1A1 (0.62)
SCHEMBL12721326 0.90 TSHR (0.52)
SCHEMBL19631542 0.87 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101023083-A Nitrogenous fused bicyclic compound TANABE SEIYAKU CO (JP) 2007-08-22 CN claimed
US-20230041069-A1 ELECTROLYTE FOR ELECTROCHEMICAL GAS SENSOR AND ELECTROCHEMICAL GAS SENSOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-02-09 US disclosed
WO-2021124222-A1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2021-06-24 WO disclosed
US-20170145020-A1 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS,COMPOSITIONS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2017-05-25 US disclosed
US-9447122-B2 Arginase inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2016-09-20 US disclosed
US-20160237086-A1 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS,COMPOSITIONS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2016-08-18 US disclosed
US-9346815-B2 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof GENENTECH, INC. (US) 2016-05-24 US disclosed
CN-102245616-B Method for producing organolithium compound and method for producing substituted aromatic compound NIPPON SODA CO.,LTD. (JP) 2016-03-30 CN disclosed
EP-2220061-B1 SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME (US) 2016-02-17 EP disclosed
US-20150336962-A1 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2015-11-26 US disclosed
US-20110123435-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY MERCK SHARP & DOHME LLC 2011-05-26 US disclosed
US-7928163-B2 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides AMBRX, INC. (US) 2011-04-19 US disclosed
CN-101106048-B Fluorophor paste and method for manufacturing display device TORAY INDUSTRIES 2011-02-16 CN disclosed
WO-2010132520-A1 SPIRO 1,3,4-THIADIAZOLINE DERIVATIVES AS KSP INHIBITORS SCHERING CORPORATION (US) 2010-11-18 WO disclosed
EP-1654257-B1 AMINOPYRONES AND THEIR USE AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2010-03-17 EP disclosed
WO-2009061597-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY SCHERING CORPORATION (US) 2009-05-14 WO disclosed
WO-2009061596-A1 COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY SCHERING CORPORATION (US) 2009-05-14 WO disclosed
WO-2009052288-A1 SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY SCHERING CORPORATION (US) 2009-04-23 WO disclosed
CN-101106048-A Fluorophor paste and method for manufacturing display device TORAY INDUSTRIES (JP) 2008-01-16 CN disclosed
CN-101023083-A Nitrogenous fused bicyclic compound TANABE SEIYAKU CO (JP) 2007-08-22 CN disclosed