Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462172 | 0.81 | KDM4E (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9020733 | 0.77 | HPGD (0.41) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL10500440 | 0.76 | CYP3A4 (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL322590 | 0.71 | PDE4A (0.52) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28467263 | 0.71 | PDE4A (0.52) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9476831 | 0.67 | KDM1A (0.44) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL17200849 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL208526 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL5538521 | 0.67 | EPHX2 (0.36) | — | |
| SCHEMBL1007150 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |