Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491755 | 0.88 | LMNA (0.54) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL5491765 | 0.88 | LMNA (0.54) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL6882664 | 0.88 | LMNA (0.54) | ALDH1A1LMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL16116975 | 0.86 | SPHK1 (0.43) | FKBP1ASPHK1 | |
| SCHEMBL15624148 | 0.86 | SPHK1 (0.43) | FKBP1ASPHK1 | |
| SCHEMBL15624129 | 0.86 | SPHK1 (0.41) | ALDH1A1LMNAACESPHK1HTR1A | |
| SCHEMBL15624144 | 0.86 | SPHK1 (0.41) | ALDH1A1LMNAACESPHK1HTR1A | |
| SCHEMBL10424382 | 0.85 | LMNA (0.44) | LMNARAB9ASMN1; SMN2PKMPOLB | |
| SCHEMBL10424383 | 0.85 | LMNA (0.44) | LMNARAB9ASMN1; SMN2PKMPOLB | |
| SCHEMBL10424384 | 0.85 | LMNA (0.44) | LMNARAB9ASMN1; SMN2PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139792-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-11-19 | — | — | WO | disclosed |
| WO-2006043145-A1 | INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-04-27 | — | — | WO | disclosed |