Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 8/20 | 0.37 |
| ▸ | THRA | P10827 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006668 | 0.80 | P2RX7 (0.44) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL7999027 | 0.79 | — | — | |
| SCHEMBL7989781 | 0.75 | THRB (0.48) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL27552165 | 0.74 | — | — | |
| SCHEMBL10421658 | 0.73 | MEN1 (0.59) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL8006662 | 0.71 | THRB (0.44) | P2RX7MEN1NR1I2KMT2ATHRB | |
| SCHEMBL7998508 | 0.71 | MEN1 (0.43) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL10394522 | 0.71 | P2RX7 (0.48) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL10395440 | 0.69 | MEN1 (0.53) | P2RX7MEN1NR1I2KMT2AABCB11 | |
| SCHEMBL5567160 | 0.67 | MEN1 (0.56) | P2RX7MEN1NR1I2KMT2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |