Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940887 | 0.88 | MAPT (0.61) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL8004203 | 0.81 | STS (0.57) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL939753 | 0.81 | STS (0.57) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL940166 | 0.80 | MMP2 (0.60) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL939804 | 0.80 | STS (0.56) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL940275 | 0.80 | STS (0.56) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL940700 | 0.77 | CA2 (0.53) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL940893 | 0.75 | CA2 (0.51) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL939812 | 0.75 | CA2 (0.53) | STSCA2MAPTALDH1A1LMNA | |
| SCHEMBL940263 | 0.72 | STS (0.68) | STSCA2ALDH1A1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118292-A1 | ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS | NOVARTIS AG (CH) | 2009-10-01 | — | — | WO | disclosed |