Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657093 | 0.94 | KMT2A (0.47) | KMT2AMEN1HTR2AHTR2CHTR2B | |
| SCHEMBL9658473 | 0.80 | MEN1 (0.38) | KMT2AMEN1ALDH1A1ALOX15EGFR | |
| SCHEMBL3163224 | 0.77 | KDM1A (0.46) | HTR2CHTR2BKDM4EGAA | |
| SCHEMBL1849372 | 0.77 | TAAR1 (0.45) | HTR2AHTR2CHTR2BALDH1A1L3MBTL1 | |
| SCHEMBL4169809 | 0.77 | TAAR1 (0.45) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL4718842 | 0.74 | KDM1A (0.49) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL8106248 | 0.74 | NOS1 (0.32) | — | |
| SCHEMBL3165666 | 0.73 | HTR2C (0.47) | KMT2AMEN1HTR2AHTR2CHTR2B | |
| SCHEMBL2201865 | 0.73 | HTR6 (0.33) | ALDH1A1MAPTL3MBTL1KDM4EEGFR | |
| SCHEMBL8646652 | 0.72 | TAAR1 (0.44) | HTR2AHTR2CHTR2BALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6105691-A | CONTAINING CAUSTIC, A NATURAL WAX, A NATURAL THINNER, GLYCEROL, PHOSPHORIC ACID AND/OR BORIC ACID FOR INCREASING DRILLING LUBRICATION, THINNING THE DRILLING MUD, DECREASING BIT BALLING AND ROCK RESISTANCE | SPECTRAL, INC. (US) | 2000-08-22 | — | — | US | disclosed |