Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL17911799 | 0.83 | TDP1 (0.58) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL21371 | 0.83 | TDP1 (0.61) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL8020302 | 0.82 | LMNA (0.44) | POLBAPEX1HTTTDP1HPGD | |
| SCHEMBL28331865 | 0.82 | TDP1 (0.60) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL44088 | 0.82 | CYP1A2 (0.54) | KMT2AMEN1THRBRAB9ANPC1 | |
| Methacrylic Acid SCHEMBL2427050 | 0.81 | POLB (0.53) | POLBAPEX1HTTTDP1KMT2A | |
| Acrylic Acid SCHEMBL2464234 | 0.81 | THRB (0.45) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL28225095 | 0.81 | POLB (0.48) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL15936108 | 0.81 | POLB (0.56) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL3861027 | 0.81 | THRB (0.54) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |