SCHEMBL8006897

SCHEMBL8006897

COC(=O)c1c(O)ccc(C)c1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.57
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA7 P43166 5/20 0.57
CA9 Q16790 5/20 0.57
CA14 Q9ULX7 5/20 0.57
CYP3A4 P08684 2/20 0.49
ACHE P22303 1/20 0.49
HPGD P15428 4/20 0.46
HSD17B10 Q99714 5/20 0.45
KDM4E B2RXH2 3/20 0.45
PDE10A Q9Y233 1/20 0.44
GAA P10253 1/20 0.43
XDH P47989 1/20 0.43
TSHR P16473 2/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10364322 0.86 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL17926325 0.82 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL27450337 0.81 CA1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL20778162 0.81 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL30856057 0.80 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL6736660 0.80 GUSB (0.45) CA12CA1CA2CA7CA9
SCHEMBL160098 0.80 CA12 (0.77) CA12CA1CA2CA7CA9
SCHEMBL2382402 0.79 ALDH1A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL29284888 0.78 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL30735951 0.77 CA12 (0.55) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0061670-B2 Process for dyeing leather and pelts with dye mixtures CIBA GEIGY AG (CH) 1994-06-01 EP disclosed
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
US-4874848-A FOR DYEING WOOL, LEATHER, POLYAMIDES BLACK OR BROWN CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
EP-0231147-A2 Process for the trichromatic dyeing of leather CIBA-GEIGY AG (CH) 1987-08-05 EP disclosed
EP-0181836-A1 Process for improving the light fastness of dyed leathers CIBA-GEIGY AG (CH) 1986-05-21 EP disclosed
EP-0048693-B1 DISAZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1986-01-08 EP disclosed
EP-0079858-B1 AZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1985-12-27 EP disclosed
EP-0087715-A1 Complex metal dyestuffs free from sulphon amide and amino groups BASF Aktiengesellschaft (DE) 1983-09-07 EP disclosed
EP-0082117-A1 Chromium complexes of polyazo dyestuffs CIBA-GEIGY AG (CH) 1983-06-22 EP disclosed
EP-0079858-A1 Azo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed
EP-0019851-B1 1:2 CHROMIUM COMPLEX DYESTUFFS OF THE AZOMETHINE AND/OR AZO SERIES, THEIR PREPARATION AND USE IN DYEING AND PRINTING POLYAMIDE OR CELLULOSE MATERIALS CIBA-GEIGY AG (CH) 1983-05-11 EP disclosed
EP-0061670-A1 Process for dyeing leather and pelts with dye mixtures CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
US-4340536-A Chrome-complex dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-07-20 US disclosed
EP-0048693-A2 Disazo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1982-03-31 EP disclosed
EP-0037377-A1 Metal-complex dyestuffs, their preparation and use CIBA-GEIGY AG (CH) 1981-10-07 EP disclosed
EP-0019851-A1 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 EP disclosed