Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 13/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 12/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330842 | 0.84 | HTT (0.43) | HTTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL8013023 | 0.77 | CA1 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2MEN1 | |
| SCHEMBL8111865 | 0.77 | GAA (0.48) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL2011531 | 0.77 | MEN1 (0.46) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL9135192 | 0.75 | HTT (0.36) | HTTSMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL9378716 | 0.75 | HTT (0.33) | HTTSMN1; SMN2PKMTSHRRECQL | |
| SCHEMBL10440650 | 0.74 | ALDH1A1 (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8437290 | 0.72 | ALDH1A1 (0.35) | TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL7024101 | 0.71 | HTT (0.48) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 | |
| SCHEMBL12695380 | 0.71 | HTT (0.61) | TAS1R3TAS1R1TAS1R2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |