Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687755 | 0.87 | HTT (0.32) | SMN1; SMN2 | |
| SCHEMBL4671913 | 0.82 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL4678354 | 0.82 | L3MBTL1 (0.39) | ALDH1A1MAPTCASP7CASP6TAS1R3 | |
| SCHEMBL9238743 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1MAPTCASP7CASP6TAS1R3 | |
| SCHEMBL4671550 | 0.77 | TAS1R3 (0.32) | ALDH1A1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL8439321 | 0.75 | TAS1R3 (0.32) | TAS1R3TAS1R1TAS1R2WDR5 | |
| SCHEMBL28241389 | 0.75 | L3MBTL1 (0.39) | ALDH1A1MAPTCASP7CASP6TAS1R3 | |
| SCHEMBL8887354 | 0.74 | TAS1R3 (0.40) | MAPTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL17468410 | 0.73 | TDP1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9087991 | 0.73 | L3MBTL1 (0.40) | ALDH1A1IMPDH2SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859026-A | ADMINISTERING AS AN ANTIBACTERIAL AGENT | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0806421-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0641793-B1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5547962-A | QUINOLONE ANTIBIOTICS | HORURIKU SEIYAKU CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0641793-A1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |