Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918474 | 0.83 | GPR119 (0.50) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL7605085 | 0.80 | GPR119 (0.47) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL16828054 | 0.79 | GPR119 (0.59) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL18176188 | 0.78 | POLB (0.59) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL8017422 | 0.78 | THRB (0.48) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL16827765 | 0.77 | MAPT (0.47) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL12539635 | 0.76 | PDE4B (0.47) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL25794242 | 0.75 | MEN1 (0.52) | GPR119MEN1KMT2AMAPTLMNA | |
| SCHEMBL16827776 | 0.74 | GPR119 (0.47) | GPR119MEN1USP2HPGDKMT2A | |
| SCHEMBL1854582 | 0.73 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037074-A1 | MUTILIN 14-ESTER DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-06-29 | — | — | WO | disclosed |