Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844079 | 0.87 | TSHR (0.30) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL3907662 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL1939866 | 0.71 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL6555303 | 0.71 | — | — | |
| SCHEMBL2816085 | 0.68 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL11329415 | 0.67 | TSHR (0.34) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL11340179 | 0.65 | ENPP2 (0.35) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL11328340 | 0.65 | ENPP2 (0.35) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL13137604 | 0.64 | ALDH1A1 (0.59) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL13101249 | 0.64 | TSHR (0.67) | TSHRALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013423-A | SILVER HALIDE PHOTOGRAPHIC MATERIAL, DEVELOPMENT AND SIX MEMBERED RING AND MERCAPTO, HYDROXYL OR OTHER GROUP ON HETERO CYCLIC COPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |