Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387289 | 0.80 | CYP1A2 (1.00) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11333910 | 0.79 | CYP1A2 (0.96) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL29475880 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1POLBMEN1APEX1 | |
| SCHEMBL197490 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1POLBMEN1APEX1 | |
| SCHEMBL8006518 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1POLBMEN1APEX1 | |
| 3-Aminobenzoic Acid SCHEMBL8008127 | 0.75 | CYP1A2 (0.66) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL24733697 | 0.75 | CYP1A2 (0.57) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL11687973 | 0.75 | CYP1A2 (0.65) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL15362559 | 0.74 | CYP1A2 (0.64) | CYP1A2CYP2C19MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL12986725 | 0.72 | NTRK1 (0.55) | CYP1A2CYP2C19MAPK1RAB9ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |