Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734141 | 0.79 | TSHR (0.50) | TSHRMAPTHTTMYCNR4A1 | |
| SCHEMBL1143383 | 0.77 | CYP1A2 (0.62) | CYP1A2CYP2C19MAPK1TSHRMAPT | |
| SCHEMBL31457163 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP2C19MAPK1MAPTRAB9A | |
| SCHEMBL1814517 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP2C19MAPK1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11473767 | 0.76 | CYP1A2 (0.61) | CYP1A2CYP2C19MAPK1TSHRMAPT | |
| SCHEMBL8007162 | 0.75 | CYP1A2 (0.64) | CYP1A2CYP2C19MAPK1MAPTRAB9A | |
| SCHEMBL9023628 | 0.75 | TSHR (0.59) | TSHRMAPTHTTMYCNR4A1 | |
| SCHEMBL394416 | 0.75 | POLB (0.56) | CYP1A2CYP2C19MAPK1MAPTMYC | |
| SCHEMBL15428589 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2C19MAPK1MAPTRAB9A | |
| SCHEMBL10925409 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2C19MAPK1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | HSPA9, ATF4, GPX4 | CYP1A2 4070/4885CYP2C19 4778/4885MAPK1 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.