SCHEMBL8007183

SCHEMBL8007183

COc1cc(OC)c(O)c(-c2cc(OC)cc(OC)c2O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.53
BCR P11274 1/20 0.53
CYP3A4 P08684 3/20 0.50
TNKS2 Q9H2K2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.50
ERN1 O75460 2/20 0.47
USP2 O75604 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ELANE P08246 1/20 0.46
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA3 P07451 1/20 0.43
PKM P14618 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1047550 0.87 ABL1 (0.65) ABL1BCRCYP3A4ALDH1A1CYP1A2
SCHEMBL4445709 0.83 CYP3A4 (0.59) ABL1BCRCYP3A4ALDH1A1ERN1
SCHEMBL18419016 0.79 ALOX5 (0.69) ABL1BCRCYP3A4ALDH1A1ERN1
SCHEMBL11581623 0.79 ABL1 (0.52) ABL1BCRCYP3A4ALDH1A1ERN1
SCHEMBL14327775 0.79 MAPT (0.47) ALDH1A1SMN1; SMN2ELANECA1CA2
SCHEMBL890469 0.78 ERN1 (0.46) ABL1BCRCYP3A4TNKS2ALDH1A1
SCHEMBL24161883 0.78 PTGS2 (0.61) CYP3A4TNKS2CA1CA2CA12
SCHEMBL7195739 0.77 ABL1 (0.50) ABL1BCRCYP3A4ALDH1A1ERN1
SCHEMBL14390273 0.77 ABL1 (0.55) ABL1BCRCYP3A4ALDH1A1CYP1A2
SCHEMBL29913371 0.77 ABL1 (0.55) ABL1BCRCYP3A4ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835751-A Phosphite ester-phosphate ester compound and preparation method and application thereof 江西苏克尔新材料有限公司 2022-08-02 CN disclosed
CN-114832860-A Olefin hydroformylation catalyst composition and preparation method and application thereof 江西苏克尔新材料有限公司 2022-08-02 CN disclosed
US-6025503-A REACTING OPTICALLY ACTIVE(OR RACEMIC) TITANIUM ALKOXIDE COMPLEXES WITH CHIRAL ACTIVATORS(ESPECIALLY DIOLS) YIELDS NEW TITANIUM COMPLEXES WHICH ARE ENANTIO-SELECTIVE IN C-C BOND FORMING REACTIONS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-02-15 US disclosed