Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226674 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRNAAATP53 | |
| SCHEMBL28638750 | 0.86 | TSHR (0.50) | LMNAALDH1A1TSHRNAAATP53 | |
| SCHEMBL541541 | 0.85 | LMNA (0.49) | LMNAALDH1A1TSHRNAAATP53 | |
| SCHEMBL16878989 | 0.83 | TSHR (0.50) | LMNAALDH1A1TSHRNAAATP53 | |
| SCHEMBL4592985 | 0.82 | SMN1; SMN2 (0.54) | LMNAALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL29069533 | 0.82 | ALDH1A1 (0.52) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL8011009 | 0.80 | HCAR2 (0.48) | ALDH1A1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL6025145 | 0.79 | TSHR (0.58) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL2564553 | 0.79 | TSHR (0.58) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL14993129 | 0.79 | TSHR (0.58) | LMNAALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066311-A | ESTERIFICATION OF CHLOROGENIC ACID WITH AN ESTERIFYING ENZYME. CAFFEIC ACID AND ITS DERIVATIVES, PRODUCED BY THIS METHOD, MAY BE USED IN SUNSCREEN COMPOSITIONS, THE CAFFEIC ACID AND ITS DERIVATIVES ABSORBING BOTH UVA AND UVB LIGHT. | ZYLEPSIS LIMITED (GB) | 2000-05-23 | — | — | US | disclosed |
| EP-0764147-A1 | PRODUCTION AND USES OF CAFFEIC ACID AND DERIVATIVES THEREOF | ZYLEPSIS LIMITED (GB) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995033706-A1 | PRODUCTION AND USES OF CAFFEIC ACID AND DERIVATIVES THEREOF | ZYLEPSIS LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |