Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420404 | 0.83 | GPBAR1 (0.52) | FFAR1AKR1B1PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL7987104 | 0.76 | PDE10A (0.43) | FFAR1AKR1B1PDE10ACYP1A2CYSLTR1 | |
| SCHEMBL15549053 | 0.72 | CYSLTR1 (0.51) | FFAR1AKR1B1PDE10ACYP1A2CYSLTR1 | |
| SCHEMBL11941307 | 0.72 | PTGS2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL15549056 | 0.71 | CYSLTR1 (0.50) | FFAR1AKR1B1PDE10ACYP1A2CYSLTR1 | |
| SCHEMBL12169108 | 0.70 | PDE10A (0.55) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL28001711 | 0.69 | PDE10A (0.51) | FFAR1AKR1B1PDE10ACYP1A2CYSLTR1 | |
| SCHEMBL3950944 | 0.69 | KCNH2 (0.61) | FFAR1AKR1B1PDE10ACYP1A2CYSLTR1 | |
| SCHEMBL3271805 | 0.68 | GPBAR1 (0.62) | FFAR1AKR1B1PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL1695706 | 0.68 | AKR1B1 (0.56) | FFAR1AKR1B1CYP1A2CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158393-A1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |