SCHEMBL8007290

SCHEMBL8007290

C=CSCc1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.47
MAPK1 P28482 1/20 0.47
VNN1 O95497 2/20 0.44
HPGD P15428 3/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
RAB9A P51151 4/20 0.40
ALDH1A1 P00352 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 3/20 0.40
IDO1 P14902 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GSK3B P49841 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3231805 0.86 IDO1 (0.45) MAPK1MEN1KMT2AL3MBTL1TDP1
SCHEMBL7995281 0.80 SRD5A2 (0.47) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL8007503 0.77 SRD5A2 (0.52) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL8495763 0.75 SRD5A2 (0.48) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL7995766 0.75 PPARG (0.51) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL9065883 0.74 SRD5A2 (0.61) SRD5A2MAPK1VNN1HPGDKMT2A
SCHEMBL11464002 0.74 SRD5A2 (0.61) SRD5A2MAPK1VNN1HPGDKMT2A
SCHEMBL5697505 0.73 SRD5A2 (0.47) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL8011247 0.73 MAPK1 (0.47) SRD5A2MAPK1VNN1HPGDPPARG
SCHEMBL8007297 0.73 VNN1 (0.48) SRD5A2MAPK1VNN1HPGDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077866-A EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS NIHON BAYER AGROCHEM K.K. (JP) 2000-06-20 US disclosed
EP-0742202-B1 Benzophenone hydrazone derivatives as insecticides BAYER AGROCHEM KK (JP) 1999-12-01 EP disclosed
EP-0742202-A2 Benzophenone hydrazone derivatives as insecticides NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP disclosed