Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075527 | 0.79 | MEN1 (0.41) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL2087734 | 0.77 | RORC (0.43) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL29482981 | 0.77 | MEN1 (0.41) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL29985411 | 0.76 | MEN1 (0.38) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL1789654 | 0.76 | MEN1 (0.38) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL17586305 | 0.76 | MEN1 (0.41) | MEN1KMT2AMAPK1APLNRTDP1 | |
| SCHEMBL23538824 | 0.75 | MEN1 (0.40) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL13804301 | 0.75 | MEN1 (0.40) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL9924136 | 0.75 | MEN1 (0.40) | MEN1KMT2AMAPK1APLNRCTSL | |
| SCHEMBL7609264 | 0.75 | MEN1 (0.37) | MEN1KMT2AMAPK1APLNRCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |