Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865316 | 0.90 | P2RX7 (0.38) | MEN1KMT2AMAPK1MIFCTSL | |
| SCHEMBL2335672 | 0.86 | KMT2A (0.38) | MEN1KMT2AMAPK1CTSLNFKB1 | |
| SCHEMBL29290043 | 0.86 | DRD2 (0.38) | MEN1KMT2AMAPK1MIFCTSL | |
| SCHEMBL15142585 | 0.86 | KMT2A (0.38) | MEN1KMT2AMAPK1CTSLNFKB1 | |
| SCHEMBL29290046 | 0.82 | DRD2 (0.41) | MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL29290052 | 0.81 | DRD2 (0.48) | CTSL | |
| Hydrochloric Acid SCHEMBL23852069 | 0.79 | MEN1 (0.33) | MEN1KMT2AMAPK1MIFCTSL | |
| SCHEMBL20575845 | 0.79 | MEN1 (0.41) | MEN1KMT2AMAPK1CTSLAPLNR | |
| SCHEMBL13839062 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL30216284 | 0.77 | MEN1 (0.40) | MEN1KMT2AMAPK1CTSLAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |