Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850817 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL677197 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL27971831 | 0.84 | MAPT (0.37) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL7677493 | 0.82 | LMNA (0.39) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL5481797 | 0.81 | ALDH1A1 (0.35) | LMNA | |
| SCHEMBL9356856 | 0.79 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17027536 | 0.79 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17027509 | 0.79 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL7990980 | 0.79 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17027570 | 0.79 | MAPT (0.41) | LMNAADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100326-A | HOMOGENEOUSLY DISPERSING 4-ISOCYANATOMETHYLOCTANE 1,8-DIISOCYANATE IN WATER WITHOUT A HYDROPHILIC AGENT FOR FORMING A SOLVENT-FREE LACQUERS AND COATING AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |