Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997965 | 0.87 | KMT2A (0.43) | CYP3A4CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8007518 | 0.87 | KMT2A (0.43) | CYP3A4CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8009438 | 0.85 | KCNH2 (0.38) | CYP3A4KCNH2 | |
| SCHEMBL8007488 | 0.84 | PIM3 (0.41) | CYP3A4CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL1855545 | 0.80 | POLB (0.46) | CYP3A4POLBKCNH2 | |
| SCHEMBL1857357 | 0.79 | KCNH2 (0.44) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9023587 | 0.79 | KCNH2 (0.44) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL13483620 | 0.78 | CACNA1F (0.53) | CYP3A4CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL6975592 | 0.77 | CACNA1F (0.40) | CYP3A4CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL12961917 | 0.76 | KCNH2 (0.53) | CYP3A4POLBKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | claimed |