Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.58 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.58 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Veratraldehyde SCHEMBL319070 | 0.86 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL29923149 | 0.86 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL28289918 | 0.86 | SRC (0.67) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL10434914 | 0.85 | SRC (0.65) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL28285734 | 0.82 | SRC (0.58) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL12904379 | 0.81 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL28023292 | 0.81 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL11039664 | 0.81 | SRC (0.61) | SRCTLR2ERN1TLR1TLR6 | |
| SCHEMBL10372830 | 0.81 | SRC (0.56) | SRCTLR2ERN1TLR1TLR6 | |
| O-Veratraldehyde SCHEMBL8706125 | 0.80 | SRC (0.59) | SRCTLR2ERN1TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377699-B2 | Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue | THE UNIVERSITY OF HONG KONG (CN) | 2019-08-13 | — | — | US | disclosed |
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | THE UNIVERSITY OF HONG KONG (CN) | 2015-05-07 | — | — | US | disclosed |
| CN-101768065-B | Method for preparing 6-dimethoxysalicylaldehyde | CHENGDU CHEMPARTNER CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-101768065-B | Method for preparing 6-dimethoxysalicylaldehyde | CHENGDU CHEMPARTNER CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-102712638-A | New phenylhydrazone derivatives and their use as pharmaceuticals | ARTERIA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101304994-B | 3-aryl-isoxazole-4-carbonyl-benzofuran derivatives | HOFFMANN LA ROCHE | 2011-06-29 | — | — | CN | disclosed |
| CN-101768065-A | Method for preparing 6-dimethoxysalicylaldehyde | HUIKAI MEDICAL DEV CHENGDU CO | 2010-07-07 | — | — | CN | disclosed |
| CN-101768065-A | Method for preparing 6-dimethoxysalicylaldehyde | HUIKAI MEDICAL DEV CHENGDU CO | 2010-07-07 | — | — | CN | disclosed |
| CN-101304994-A | 3-aryl-isoxazole-4-carbonyl-benzofuran derivatives | HOFFMANN LA ROCHE (CH) | 2008-11-12 | — | — | CN | disclosed |
| WO-2000015605-A2 | CHIRAL CYANOAMINES AND METHODS OF PREPARATION | TRUSTEES OF BOSTON COLLEGE (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1998010286-A1 | METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377699-B2 | Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue | SCD, SCD5, FASN | SRC 715/4885TLR2 776/4885ERN1 2339/4885 |
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | SCD, SCD5, FASN | SRC 726/4885TLR2 790/4885ERN1 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.