Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001035 | 0.87 | L3MBTL1 (0.34) | LIPCLIPGL3MBTL1HDAC1HDAC8 | |
| SCHEMBL8000609 | 0.86 | L3MBTL1 (0.33) | LIPCLIPGL3MBTL1HDAC1HDAC8 | |
| SCHEMBL7998577 | 0.84 | L3MBTL1 (0.32) | LIPCLIPGL3MBTL1HDAC1HDAC8 | |
| SCHEMBL7998444 | 0.83 | L3MBTL1 (0.32) | LIPCLIPGL3MBTL1HDAC1HDAC8 | |
| SCHEMBL10293095 | 0.83 | TP53 (0.32) | — | |
| SCHEMBL8005068 | 0.81 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL10292761 | 0.80 | — | — | |
| SCHEMBL8009276 | 0.80 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL7998527 | 0.79 | GRIN1 (0.35) | HDAC1HDAC8HDAC6 | |
| SCHEMBL8000613 | 0.76 | L3MBTL1 (0.32) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134987-A1 | DIFLUOROMETHYL-CONTAINING MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |