Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007712 | 0.87 | KLK7 (0.37) | SYKKLK7KLK5ABCB1SLC15A1 | |
| SCHEMBL7737502 | 0.78 | CA1 (0.51) | SYKALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL5557245 | 0.78 | CA1 (0.51) | SYKALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL18429584 | 0.78 | SYK (0.50) | SYKALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL6840857 | 0.77 | SMN1; SMN2 (0.52) | SYKL3MBTL1MAPTAKT1SMN1; SMN2 | |
| SCHEMBL418232 | 0.76 | ALDH1A1 (0.51) | SYKALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL7156418 | 0.75 | SMN1; SMN2 (0.52) | SYKL3MBTL1MAPTAKT1SMN1; SMN2 | |
| SCHEMBL14768484 | 0.75 | ALDH1A1 (0.43) | SYKKLK7KLK5ABCB1SLC15A1 | |
| SCHEMBL14439276 | 0.75 | SYK (0.39) | SYKALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL8046788 | 0.75 | SYK (0.39) | SYKALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058269-A1 | DTPA ESTERS WITH ORTHOGONAL REMOVABLE PROTECTING GROUPS | MALLINCKRODT INC. (US) | 2000-10-05 | — | — | WO | disclosed |