Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783835 | 0.98 | NR5A1 (0.50) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL7072893 | 0.88 | NR5A1 (0.58) | NR5A1RARBLTA4HTSHRPTPN11 | |
| SCHEMBL7072904 | 0.88 | NR5A1 (0.58) | NR5A1RARBLTA4HTSHRPTPN11 | |
| SCHEMBL11016291 | 0.88 | LTA4H (0.53) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL7175692 | 0.88 | CYP2C19 (0.46) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL1459163 | 0.88 | TSHR (0.48) | CYP19A1CYP2C9CYP2C19CYP1A2NR5A1 | |
| SCHEMBL11327014 | 0.88 | RARB (0.40) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL15067951 | 0.87 | LTA4H (0.44) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL2222934 | 0.86 | NQO1 (0.42) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL3931754 | 0.85 | CYP1A2 (0.40) | CYP19A1CYP2C9CYP2C19CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162798-A | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2000-12-19 | — | — | US | claimed |