Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532102 | 0.92 | NQO1 (0.50) | NQO1CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL8007736 | 0.86 | CYP19A1 (0.48) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7078066 | 0.85 | LTA4H (0.50) | GAAALDH1A1LTA4HRAB9ANPC1 | |
| SCHEMBL9783835 | 0.85 | NR5A1 (0.50) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8527534 | 0.84 | NQO1 (0.45) | NQO1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6382918 | 0.84 | CYP11B1 (0.44) | NQO1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8187884 | 0.84 | ALDH1A1 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL15066586 | 0.84 | KMT2A (0.42) | KDM4ELTA4HMAPTL3MBTL1TSHR | |
| SCHEMBL17536735 | 0.83 | MAPT (0.39) | NQO1CYP19A1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9700067 | 0.82 | CYP2D6 (0.49) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084503-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |