Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 19/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008414 | 0.91 | ADRA1A (0.45) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7955792 | 0.90 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7955794 | 0.90 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7965948 | 0.84 | ADRA1A (0.43) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7968224 | 0.82 | ADRA1A (0.41) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7967885 | 0.81 | ADRA1A (0.51) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7967882 | 0.81 | ADRA1A (0.51) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7968147 | 0.79 | ADRA1A (0.39) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL8150536 | 0.79 | ADRA1A (0.39) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7077899 | 0.77 | ADRA1A (0.42) | ADRA1AADRA1BADRA1DHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143750-A | NITROGEN HETEROCYCLIC COMPOUNDS AS ENZYME INHIBITORS, FOR PROSTATE PROBLEMS AND MUSCLE RELAXANTS | MERCK & CO., INC. (US) | 2000-11-07 | — | — | US | disclosed |