Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.49 |
| ▸ | FNTB | P49356 | 4/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095345 | 0.78 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL8444571 | 0.78 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL7453431 | 0.75 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL7521521 | 0.75 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL7973895 | 0.71 | CYP11B1 (0.55) | FNTAFNTBPGGT1BCYP2C19 | |
| Hydrochloric Acid SCHEMBL7841131 | 0.69 | FNTA (0.50) | FNTAFNTBPGGT1BCYP2C19 | |
| SCHEMBL6913120 | 0.68 | FNTA (0.55) | FNTAFNTBPGGT1BCYP2D6TSHR | |
| SCHEMBL7593487 | 0.67 | CYP11B1 (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL8535449 | 0.67 | GPBAR1 (0.48) | FNTAFNTBPGGT1BCYP3A4CYP2C9 | |
| SCHEMBL8097241 | 0.67 | GPBAR1 (0.48) | FNTAFNTBPGGT1BCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019530-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-1009854-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000016626-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999010524-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999010523-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |