Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973895 | 0.84 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| Hydrochloric Acid SCHEMBL7844423 | 0.83 | AR (0.50) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| Hydrochloric Acid SCHEMBL7841131 | 0.81 | FNTA (0.50) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| SCHEMBL7464878 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| SCHEMBL5891953 | 0.74 | FNTA (0.52) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| SCHEMBL8185357 | 0.74 | CYP19A1 (0.41) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| SCHEMBL7855826 | 0.73 | LMNA (0.59) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13686774 | 0.71 | CCNC (0.49) | CYP11B1CYP11B2CYP19A1ARFNTA | |
| Hydrochloric Acid SCHEMBL7977431 | 0.71 | DCTPP1 (0.48) | CYP11B1CYP11B2CYP19A1ARPTGDR2 | |
| SCHEMBL7195630 | 0.70 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1ARFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020072081-A1 | Geranylgeranyl transferase inhibitor screening assay | ENG WAI-SI (US) | 2002-06-13 | — | — | US | disclosed |
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072081-A1 | Geranylgeranyl transferase inhibitor screening assay | GGT1, FNTA, GGPS1 | CYP11B1 917/4885CYP11B2 1457/4885CYP19A1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.