Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.48 |
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | ERG | P11308 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097241 | 1.00 | GPBAR1 (0.48) | GPBAR1FNTAFNTBPGGT1BCHRM4 | |
| SCHEMBL8097422 | 0.89 | GPBAR1 (0.49) | GPBAR1FNTAFNTBPGGT1BCHRM4 | |
| SCHEMBL8434674 | 0.89 | GPBAR1 (0.49) | GPBAR1FNTAFNTBPGGT1BCHRM4 | |
| SCHEMBL446562 | 0.85 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL8097236 | 0.85 | CCR5 (0.44) | GPBAR1FNTAFNTBPGGT1BCHRM4 | |
| SCHEMBL8534261 | 0.82 | FNTA (0.48) | GPBAR1FNTAFNTBPGGT1BTP53 | |
| SCHEMBL8095893 | 0.82 | FNTA (0.48) | GPBAR1FNTAFNTBPGGT1BTP53 | |
| SCHEMBL8433745 | 0.82 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL8095475 | 0.82 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL8444571 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1BCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |