Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013744 | 0.78 | MAPT (0.32) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL361527 | 0.77 | MAPT (0.38) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL2969079 | 0.73 | KDM4E (0.49) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL2964668 | 0.72 | PTGS1 (0.36) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL2964035 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNATP53HPGD | |
| SCHEMBL8007959 | 0.72 | KDM4E (0.57) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8007952 | 0.72 | KDM4E (0.57) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| Dimethylamine SCHEMBL8007963 | 0.71 | ALDH1A1 (0.32) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL10279750 | 0.69 | PDE4D (0.42) | TP53POLB | |
| SCHEMBL2964739 | 0.67 | SLC16A3 (0.37) | NPC1RAB9AKDM4EHCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000119274-A | TRIAZOLOPYRIMIDINE DERIVATIVE | NIPPON BAYER AGROCHEM CO LTD | 2000-04-25 | — | — | JP | disclosed |
| WO-2000009508-A1 | TRIAZOLOPYRIMIDINE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-02-24 | — | — | WO | disclosed |