Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007279 | 0.83 | NPC1 (0.39) | MAPK14ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL8009664 | 0.83 | ALDH1A1 (0.38) | MAPK14ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL7997383 | 0.82 | PGR (0.47) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL8009560 | 0.81 | GRIN1 (0.40) | MAPK14ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL8009389 | 0.80 | GRIN1 (0.49) | ALDH1A1SMN1; SMN2KDM4EPOLBHTT | |
| SCHEMBL27432293 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL9033850 | 0.72 | B3GNT2 (0.46) | ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL22783988 | 0.70 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL6177219 | 0.69 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL9032760 | 0.69 | GRIN1 (0.52) | MAPK14ALDH1A1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165941-A | Substituted 2-phenylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |