Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 8/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 6/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | BMP1 | P13497 | 7/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.41 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012489 | 0.83 | BMP1 (0.47) | PTGESMMP2MMP9MMP1MMP13 | |
| SCHEMBL8014858 | 0.81 | MMP2 (0.45) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL27547037 | 0.80 | BMP1 (0.58) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7451098 | 0.80 | BMP1 (0.58) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL8012719 | 0.78 | BMP1 (0.49) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL8011729 | 0.77 | BMP1 (0.48) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL8016090 | 0.77 | BMP1 (0.49) | MMP2MMP9MMP3MMP1MMP13 | |
| Water SCHEMBL8018798 | 0.76 | BMP1 (0.49) | MMP2MMP9MMP3MMP1MMP13 | |
| Hydrochloric Acid SCHEMBL8003281 | 0.76 | BMP1 (0.47) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL8011731 | 0.76 | MMP2 (0.44) | MMP2MMP9MMP3MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | claimed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |