Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632874 | 0.96 | — | — | |
| Trimethylammonium SCHEMBL3147628 | 0.84 | CA2 (0.50) | CA2TSHRTDP1 | |
| Sulfuric Acid SCHEMBL2018273 | 0.81 | CA2 (0.91) | CA2CA5ACA5BTSHRTDP1 | |
| Sulfuric Acid SCHEMBL10426930 | 0.81 | CA2 (0.91) | CA2CA5ACA5BTSHRTDP1 | |
| Dioxane SCHEMBL6720843 | 0.80 | CA2 (0.45) | CA2 | |
| Sulfuric Acid SCHEMBL199894 | 0.77 | CA2 (0.83) | CA2CA5ACA5BTSHRTDP1 | |
| Sulfuric Acid SCHEMBL13370066 | 0.77 | CA2 (0.83) | CA2CA5ACA5BTSHRTDP1 | |
| Sulfuric Acid SCHEMBL11761606 | 0.77 | CA2 (0.83) | CA2CA5ACA5BTSHRTDP1 | |
| SCHEMBL9727127 | 0.76 | CA2 (1.00) | CA2CA5ACA5BTSHRTDP1 | |
| SCHEMBL7217 | 0.76 | CA2 (1.00) | CA2CA5ACA5BTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000016737-A1 | COMPOSITION AND METHOD FOR WHITENING TEETH WITHOUT DAMAGING SOFT TISSUE | MCLAUGHLIN GERALD G (US) | 2000-03-30 | — | — | WO | disclosed |